Enterprise DNA Enterprise DNA
O Open Source Frameworks medium

AutoGen

by Microsoft

Microsoft's framework for multi-agent conversations. Agents that talk to each other to solve hard problems.

A

OSS

AutoGen

Added 17 May 2026

#framework #multi-agent #microsoft #python #open-source

Overview

AutoGen is Microsoft's open-source framework for building multi-agent applications. The core abstraction is a conversation between agents, each with a role and tools, coordinated by a manager or by structured patterns. Heavy Python focus, with a newer .NET sibling for the Microsoft stack.

Best for

Best for
Teams comfortable with multi-agent patterns, on Python or .NET

Use cases

  • Multi-agent code generation with reviewer and executor roles
  • Research workflows with a planner-researcher-writer triad
  • Hybrid human-in-the-loop conversational agents
  • Education and reference for multi-agent patterns

Notes

Why it matters

AutoGen helped establish the multi-agent-as-conversation pattern that most other frameworks now reference. The research lineage still drives the state of the art.

How teams use it in production

Two agents and a clear handoff outperforms five agents and a complex manager. AutoGen rewards the smaller crew.

What to watch

The split between AutoGen Studio (visual) and AutoGen Core (library) will decide whether AutoGen lands in the enterprise the way the team intends.

Pros

  • Strong research backing and influential reference patterns
  • Multi-agent conversations are first-class, not bolted on
  • Active community and ecosystem
  • .NET sibling unlocks Microsoft-stack adoption

Cons

  • Conversation-as-control-flow can be hard to debug at scale
  • Less explicit state than LangGraph
  • API surface has churned across versions

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