longevity-genie/biothings-mcp

Overview

A Model Context Protocol server that exposes biothings APIs to AI agents. It lets LLMs query biomedical data sources like gene annotations, variant information, and drug interactions through a standardized interface.

Best for

Best for
Developers building AI agents that need to query biomedical databases programmatically

Use cases

• Retrieve gene function and pathway data for research analysis
• Look up drug-target interactions and adverse effects
• Query variant annotations for genomic interpretation

How to use

Install

uvx biothings-mcp

Tools exposed

• GeneTools
• VariantTools
• ChemTools
• TaxonTools
• DownloadTools

Tested with

Claude Desktop, Cursor, Windsurf, VS Code

Example client config

{\n  "servers": [\n    {\n      "name": "biothings-mcp",\n      "url": "http://localhost:3001/mcp"\n    }\n  ]\n}

Notes

A Model Context Protocol server that exposes biothings APIs to AI agents. It lets LLMs query biomedical data sources like gene annotations, variant information, and drug interactions through a standardized interface.

32 stars on GitHub. Last updated 2025-11-03. Licensed MIT.

Use cases

• Retrieve gene function and pathway data for research analysis
• Look up drug-target interactions and adverse effects
• Query variant annotations for genomic interpretation

Pros

• Standard MCP interface makes it easy to integrate with any MCP-compatible client
• Direct access to multiple biothings databases without custom API code
• Lightweight Python server with minimal dependencies

Cons

• Small community with only 32 GitHub stars and limited documentation
• Requires running a local server, adding deployment overhead
• Dependent on external biothings API availability and rate limits

Indexed from awesome-mcp-servers-punkpeye and enriched against its public facts.