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musharna/plant-genomics-mcp

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Plant genomics MCP server — 32 tools across 11 backends (Ensembl Plants, Phytozome, UniProt, Europe PMC, QuickGO, NCBI BLAST, Gramene, KEGG, STRING-DB, ATTED-II, BAR) + cross-sourc

MCP

musharna/plant-genomics-mcp

Added 8 June 2026

#bioinformatics #ensembl-plants #genomics #kegg #llm-tools #mcp #model-context-protocol #plant-genomics

Overview

A Model Context Protocol server that exposes 32 plant genomics tools across 11 backends including Ensembl Plants, Phytozome, UniProt, Europe PMC, QuickGO, NCBI BLAST, Gramene, KEGG, STRING-DB, ATTED-II, and BAR. It supports stdio and Streamable-HTTP transports and can synthesize results across sources.

Best for

Best for
Developers building AI agents or pipelines that need unified access to plant genomics data

Use cases

  • Query gene annotations and sequences from multiple plant genomics databases via a single interface
  • Run BLAST searches against plant genomes and retrieve functional enrichment data
  • Cross-reference gene identifiers and pathway data across Ensembl, KEGG, and STRING-DB

How to use

Install

pipx install plant-genomics-mcp

Tools exposed

  • analyze_locus
  • find_homologs
  • biological_context
  • streamable-HTTP
  • PLANT_GENOMICS_MCP_HTTP_TOKEN
  • PLANT_GENOMICS_MCP_NCBI_EMAIL
  • PLANT_GENOMICS_MCP_HTTP_HOST
  • PLANT_GENOMICS_MCP_HTTP_PORT
  • PLANT_GENOMICS_MCP_HTTP_MAX_BODY
  • PLANT_GENOMICS_MCP_HTTP_STATELESS
  • PLANT_GENOMICS_MCP_HTTP_JSON
  • PLANT_GENOMICS_MCP_BLAST_CONCURRENCY
  • PLANT_GENOMICS_MCP_CACHE_TTL
  • PLANT_GENOMICS_MCP_CACHE_SIZE
  • PLANT_GENOMICS_MCP_CACHE_DISABLED
  • ensembl_plants_lookup_locus
  • get_gene_xrefs
  • phytozome_lookup_locus
  • resolve_locus_to_uniprot
  • locus_literature

Tested with

Claude Code

Notes

A Model Context Protocol server that exposes 32 plant genomics tools across 11 backends including Ensembl Plants, Phytozome, UniProt, Europe PMC, QuickGO, NCBI BLAST, Gramene, KEGG, STRING-DB, ATTED-II, and BAR. It supports stdio and Streamable-HTTP transports and can synthesize results across sources.

0 stars on GitHub. Last updated 2026-06-07. Licensed MIT.

Use cases

  • Query gene annotations and sequences from multiple plant genomics databases via a single interface
  • Run BLAST searches against plant genomes and retrieve functional enrichment data
  • Cross-reference gene identifiers and pathway data across Ensembl, KEGG, and STRING-DB

Pros

  • Covers a wide range of major plant genomics databases in one tool
  • Supports both local stdio and HTTP streaming transports for flexible integration
  • Cross-source synthesis reduces manual data merging

Cons

  • Zero stars and no community traction yet
  • Requires running a Python MCP server, adding deployment overhead
  • Dependence on external APIs means reliability varies by backend uptime

Indexed from awesome-mcp-servers-punkpeye and enriched against its public facts.

Pros

  • Covers a wide range of major plant genomics databases in one tool
  • Supports both local stdio and HTTP streaming transports for flexible integration
  • Cross-source synthesis reduces manual data merging

Cons

  • Zero stars and no community traction yet
  • Requires running a Python MCP server, adding deployment overhead
  • Dependence on external APIs means reliability varies by backend uptime

Pairs with

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